Review



myriocin, an inhibitor of serine palmitoyl-transferase (spt), a key enzyme for ceramide de novo synthesis  (Cayman Chemical)


Bioz Verified Symbol Cayman Chemical is a verified supplier  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 90
      Buy from Supplier

    Structured Review

    Cayman Chemical myriocin, an inhibitor of serine palmitoyl-transferase (spt), a key enzyme for ceramide de novo synthesis
    Myriocin, An Inhibitor Of Serine Palmitoyl Transferase (Spt), A Key Enzyme For Ceramide De Novo Synthesis, supplied by Cayman Chemical, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/ceramide+synthesis+inhibitors/myriocin++an+inhibitor+of+serine+palmitoyl+transferase++spt+++a+key+enzyme+for+ceramide+de+novo+synthesis/pmc10054354-116-13-27
    Average 90 stars, based on 1 article reviews
    myriocin, an inhibitor of serine palmitoyl-transferase (spt), a key enzyme for ceramide de novo synthesis - by Bioz Stars, 2026-09
    90/100 stars

    Images

    Related Articles

    other:

    Article Title: Cigarette smoke exposure impairs β-cell function through activation of oxidative stress and ceramide accumulation
    Article Snippet: Ceramide synthesis inhibitors were purchased from Cayman chemical (An Arbor, MI).



    Similar Products

    ceramide synthesis inhibitors  (Croda International Plc)
    98
    Croda International Plc ceramide synthesis inhibitors
    Ceramide Synthesis Inhibitors, supplied by Croda International Plc, used in various techniques. Bioz Stars score: 98/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/ceramide+synthesis+inhibitors/Ceramide/pm41325527-434-24-62
    Average 98 stars, based on 1 article reviews
    ceramide synthesis inhibitors - by Bioz Stars, 2026-09
    98/100 stars
    		  Buy from Supplier
    myriocin, an inhibitor of serine palmitoyl-transferase (spt), a key enzyme for ceramide de novo synthesis  (Cayman Chemical)
    90
    Cayman Chemical myriocin, an inhibitor of serine palmitoyl-transferase (spt), a key enzyme for ceramide de novo synthesis
    Myriocin, An Inhibitor Of Serine Palmitoyl Transferase (Spt), A Key Enzyme For Ceramide De Novo Synthesis, supplied by Cayman Chemical, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/ceramide+synthesis+inhibitors/myriocin++an+inhibitor+of+serine+palmitoyl+transferase++spt+++a+key+enzyme+for+ceramide+de+novo+synthesis/pmc10054354-116-13-27
    Average 90 stars, based on 1 article reviews
    myriocin, an inhibitor of serine palmitoyl-transferase (spt), a key enzyme for ceramide de novo synthesis - by Bioz Stars, 2026-09
    90/100 stars
    		  Buy from Supplier
    ceramide synthesis inhibitor fumonisin b1  (Millipore)
    90
    Millipore ceramide synthesis inhibitor fumonisin b1
    ERBB2-positive cells' sensitivity to palmitate is through ROS formation and <t>ceramide</t> production. (a) BT474 and MDA-MB-361 cells were treated with vehicle or 20 μmol/l GW9662 together with 0, 0.5, and 1 μmol/l of N -acetyl-cysteine (NAC) for 72 hours. Live cells were counted and presented as percentage of the GW9662 control. Error bars indicate the standard deviation from three individual experiments. *** P < 0.05. (b) BT474 and MDA-MB-361 cells were treated with vehicle or 20 μmol/l GW9662 together with 0 and 10 μmol/l of the ceramide synthesis inhibitor <t>fumonisin</t> <t>B1</t> for 72 hours. Live cells were counted and presented as percentage of the GW9662 control. Error bars indicate the standard deviation from three individual experiments. ROS, reactive oxygen species.
    Ceramide Synthesis Inhibitor Fumonisin B1, supplied by Millipore, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/ceramide+synthesis+inhibitors/ceramide+synthase+inhibitor+fumonisin+b1/pmc02688944-43-10-18
    Average 90 stars, based on 1 article reviews
    ceramide synthesis inhibitor fumonisin b1 - by Bioz Stars, 2026-09
    90/100 stars
    		  Buy from Supplier
    ceramide synthesis inhibitors  (Cayman Chemical)
    90
    Cayman Chemical ceramide synthesis inhibitors
    ERBB2-positive cells' sensitivity to palmitate is through ROS formation and <t>ceramide</t> production. (a) BT474 and MDA-MB-361 cells were treated with vehicle or 20 μmol/l GW9662 together with 0, 0.5, and 1 μmol/l of N -acetyl-cysteine (NAC) for 72 hours. Live cells were counted and presented as percentage of the GW9662 control. Error bars indicate the standard deviation from three individual experiments. *** P < 0.05. (b) BT474 and MDA-MB-361 cells were treated with vehicle or 20 μmol/l GW9662 together with 0 and 10 μmol/l of the ceramide synthesis inhibitor <t>fumonisin</t> <t>B1</t> for 72 hours. Live cells were counted and presented as percentage of the GW9662 control. Error bars indicate the standard deviation from three individual experiments. ROS, reactive oxygen species.
    Ceramide Synthesis Inhibitors, supplied by Cayman Chemical, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/ceramide+synthesis+inhibitors/ceramide+synthesis+inhibitors/pmc07170997__mmc1-38-0-6
    Average 90 stars, based on 1 article reviews
    ceramide synthesis inhibitors - by Bioz Stars, 2026-09
    90/100 stars
    		  Buy from Supplier
    inhibitor of ceramide synthesis gw4869  (Millipore)
    90
    Millipore inhibitor of ceramide synthesis gw4869
    ERBB2-positive cells' sensitivity to palmitate is through ROS formation and <t>ceramide</t> production. (a) BT474 and MDA-MB-361 cells were treated with vehicle or 20 μmol/l GW9662 together with 0, 0.5, and 1 μmol/l of N -acetyl-cysteine (NAC) for 72 hours. Live cells were counted and presented as percentage of the GW9662 control. Error bars indicate the standard deviation from three individual experiments. *** P < 0.05. (b) BT474 and MDA-MB-361 cells were treated with vehicle or 20 μmol/l GW9662 together with 0 and 10 μmol/l of the ceramide synthesis inhibitor <t>fumonisin</t> <t>B1</t> for 72 hours. Live cells were counted and presented as percentage of the GW9662 control. Error bars indicate the standard deviation from three individual experiments. ROS, reactive oxygen species.
    Inhibitor Of Ceramide Synthesis Gw4869, supplied by Millipore, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/ceramide+synthesis+inhibitors/gw4869/pm25557794-77-18-30
    Average 90 stars, based on 1 article reviews
    inhibitor of ceramide synthesis gw4869 - by Bioz Stars, 2026-09
    90/100 stars
    		  Buy from Supplier
    myriocin, a serine palmitoyltransferase inhibitor of the de novo ceramide synthesis pathway  (Biomol GmbH)
    90
    Biomol GmbH myriocin, a serine palmitoyltransferase inhibitor of the de novo ceramide synthesis pathway
    ERBB2-positive cells' sensitivity to palmitate is through ROS formation and <t>ceramide</t> production. (a) BT474 and MDA-MB-361 cells were treated with vehicle or 20 μmol/l GW9662 together with 0, 0.5, and 1 μmol/l of N -acetyl-cysteine (NAC) for 72 hours. Live cells were counted and presented as percentage of the GW9662 control. Error bars indicate the standard deviation from three individual experiments. *** P < 0.05. (b) BT474 and MDA-MB-361 cells were treated with vehicle or 20 μmol/l GW9662 together with 0 and 10 μmol/l of the ceramide synthesis inhibitor <t>fumonisin</t> <t>B1</t> for 72 hours. Live cells were counted and presented as percentage of the GW9662 control. Error bars indicate the standard deviation from three individual experiments. ROS, reactive oxygen species.
    Myriocin, A Serine Palmitoyltransferase Inhibitor Of The De Novo Ceramide Synthesis Pathway, supplied by Biomol GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/ceramide+synthesis+inhibitors/myriocin++a+serine+palmitoyltransferase+inhibitor+of+the+de+novo+ceramide+synthesis+pathway/pmc02976739-16-0-15
    Average 90 stars, based on 1 article reviews
    myriocin, a serine palmitoyltransferase inhibitor of the de novo ceramide synthesis pathway - by Bioz Stars, 2026-09
    90/100 stars
    		  Buy from Supplier
    ceramide synthesis inhibitors gw4869  (Millipore)
    90
    Millipore ceramide synthesis inhibitors gw4869
    ERBB2-positive cells' sensitivity to palmitate is through ROS formation and <t>ceramide</t> production. (a) BT474 and MDA-MB-361 cells were treated with vehicle or 20 μmol/l GW9662 together with 0, 0.5, and 1 μmol/l of N -acetyl-cysteine (NAC) for 72 hours. Live cells were counted and presented as percentage of the GW9662 control. Error bars indicate the standard deviation from three individual experiments. *** P < 0.05. (b) BT474 and MDA-MB-361 cells were treated with vehicle or 20 μmol/l GW9662 together with 0 and 10 μmol/l of the ceramide synthesis inhibitor <t>fumonisin</t> <t>B1</t> for 72 hours. Live cells were counted and presented as percentage of the GW9662 control. Error bars indicate the standard deviation from three individual experiments. ROS, reactive oxygen species.
    Ceramide Synthesis Inhibitors Gw4869, supplied by Millipore, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/ceramide+synthesis+inhibitors/gw4869/pm16189296-38-1-6
    Average 90 stars, based on 1 article reviews
    ceramide synthesis inhibitors gw4869 - by Bioz Stars, 2026-09
    90/100 stars
    		  Buy from Supplier
    ceramide synthesis inhibitor gw4869  (Millipore)
    90
    Millipore ceramide synthesis inhibitor gw4869
    ERBB2-positive cells' sensitivity to palmitate is through ROS formation and <t>ceramide</t> production. (a) BT474 and MDA-MB-361 cells were treated with vehicle or 20 μmol/l GW9662 together with 0, 0.5, and 1 μmol/l of N -acetyl-cysteine (NAC) for 72 hours. Live cells were counted and presented as percentage of the GW9662 control. Error bars indicate the standard deviation from three individual experiments. *** P < 0.05. (b) BT474 and MDA-MB-361 cells were treated with vehicle or 20 μmol/l GW9662 together with 0 and 10 μmol/l of the ceramide synthesis inhibitor <t>fumonisin</t> <t>B1</t> for 72 hours. Live cells were counted and presented as percentage of the GW9662 control. Error bars indicate the standard deviation from three individual experiments. ROS, reactive oxygen species.
    Ceramide Synthesis Inhibitor Gw4869, supplied by Millipore, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/ceramide+synthesis+inhibitors/gw4869/pm16189296-73-1-6
    Average 90 stars, based on 1 article reviews
    ceramide synthesis inhibitor gw4869 - by Bioz Stars, 2026-09
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    ERBB2-positive cells' sensitivity to palmitate is through ROS formation and ceramide production. (a) BT474 and MDA-MB-361 cells were treated with vehicle or 20 μmol/l GW9662 together with 0, 0.5, and 1 μmol/l of N -acetyl-cysteine (NAC) for 72 hours. Live cells were counted and presented as percentage of the GW9662 control. Error bars indicate the standard deviation from three individual experiments. *** P < 0.05. (b) BT474 and MDA-MB-361 cells were treated with vehicle or 20 μmol/l GW9662 together with 0 and 10 μmol/l of the ceramide synthesis inhibitor fumonisin B1 for 72 hours. Live cells were counted and presented as percentage of the GW9662 control. Error bars indicate the standard deviation from three individual experiments. ROS, reactive oxygen species.

    Journal: Breast Cancer Research : BCR

    Article Title: Peroxisome proliferator-activated receptor-γ protects ERBB2-positive breast cancer cells from palmitate toxicity

    doi: 10.1186/bcr2240

    Figure Lengend Snippet: ERBB2-positive cells' sensitivity to palmitate is through ROS formation and ceramide production. (a) BT474 and MDA-MB-361 cells were treated with vehicle or 20 μmol/l GW9662 together with 0, 0.5, and 1 μmol/l of N -acetyl-cysteine (NAC) for 72 hours. Live cells were counted and presented as percentage of the GW9662 control. Error bars indicate the standard deviation from three individual experiments. *** P < 0.05. (b) BT474 and MDA-MB-361 cells were treated with vehicle or 20 μmol/l GW9662 together with 0 and 10 μmol/l of the ceramide synthesis inhibitor fumonisin B1 for 72 hours. Live cells were counted and presented as percentage of the GW9662 control. Error bars indicate the standard deviation from three individual experiments. ROS, reactive oxygen species.

    Article Snippet: The PPARγ antagonist GW9662, the fatty acid palmitate, and the ceramide synthesis inhibitor fumonisin B1 were obtained from Sigma-Aldrich (St. Louis, MO, USA).

    Techniques: Standard Deviation